Occipital nerve block ยท St. Louis
If numbing the two occipital nerves at the back of your skull stops the headache, you have just found out where to aim next.
A greater or lesser occipital nerve block numbs the nerves that run from the base of the skull over the scalp. It treats occipital neuralgia and cervicogenic headache directly. It also tells us whether those nerves are the real source of a headache that has been guessed at for years.

What does an occipital nerve block treat?
The greater and lesser occipital nerves come out of the upper neck. They run up over the back and side of the scalp. Sometimes they get irritated. The cause is tight muscles gripping down on them, degenerative changes (joints breaking down) in the upper neck, or no structural reason we can find at all. The result is occipital neuralgia: sharp, shocking or burning pain that starts at the base of the skull and can spread forward. Cervicogenic headache is a related but different problem. Here the pain actually starts in the joints and discs of the upper neck. You feel it in the head because the nerve paths for neck signals and head signals meet in the same part of the spinal cord. The two are often confused with each other, and both are often confused with migraine.
The two nerves
GREATER OCCIPITAL NERVE
The larger of the two, closer to the middle, supplying most of the back of the scalp. It is involved in the large majority of the occipital neuralgia and cervicogenic headache cases we see, and it is usually blocked first.
LESSER OCCIPITAL NERVE
Smaller, further to the side, supplying the side of the scalp behind the ear. Blocked along with the greater nerve when the pain pattern or exam points to its territory.
Can an occipital nerve block show what is causing my headache?
Naming a headache by history and exam alone is truly hard. Occipital neuralgia, cervicogenic headache and migraine can all cause pain in the same places. Patients are often treated for one when the exam actually points to another. A block answers the question directly. If numbing the occipital nerves substantially relieves the headache within minutes, the occipital pathway is involved, whatever else may also be going on. If it does very little, the pain is being generated somewhere the block cannot reach. Treating it as an occipital problem then wastes time that could go toward the right diagnosis.
What a block that works tells you about the next step
A single block that gives real relief is useful on its own. For many patients, repeating it from time to time is a reasonable, low-risk plan. For headaches that keep coming back on a set schedule, a positive block is also the gate to two longer-acting options. One is radiofrequency ablation of the occipital nerve. It stretches relief from hours to months by disrupting the nerve’s ability to carry a signal. The other, for headaches frequent and severe enough to justify an implant, is peripheral nerve stimulation placed along the same nerve. Neither is offered to someone who has not first shown a clear, repeatable response to the block. The block is the audition, not a formality before a procedure we had already decided to do.
The terrain behind a headache that will not quit
A single irritated nerve rarely explains why a headache has become a daily event. Tight muscles at the base of the skull — the suboccipital group — are one mechanical driver. A second, biological one makes it worse: body-wide inflammation and poor sleep both lower the point at which any nerve, occipital or otherwise, fires a pain signal. Add a desk job or a phone habit that holds your neck bent forward for hours at a time. Now the posture and social piece is doing as much work as the two biological ones. A block quiets the nerve. It does not change the posture or the sleep debt that keep irritating it again — which is why this practice pairs occipital treatment with an honest look at sleep and movement rather than treating the nerve in isolation.
Does an occipital nerve block work?
A 2021 systematic review of greater occipital nerve block for cervicogenic headache found consistent short-term benefit across the studies. But study quality and technique varied. So the review stopped short of backing one exact protocol as best. A separate narrative review of occipital nerve block across headache disorders reached a similar finding. The block works acutely, and as a diagnostic tool, with fair consistency. The evidence on how long relief lasts, and how it compares head to head with other headache treatments, is thinner and more mixed. A 2026 systematic review of occipital neuralgia treatments noted that most published series are small and retrospective (looking back at past cases). That is typical for a condition this uncommon, and one each study defines a bit differently.
What that means in practice: we treat a positive block as strong, personal evidence — you responded, not a made-up patient in a paper. We are also honest about the limits. The published research cannot yet tell us exactly which patients will need only occasional blocks versus ablation versus a stimulator. That decision gets made by watching how your own headaches respond over time, not by a population average.
What happens during an occipital nerve block?
- Headache pattern and pain map reviewed, including what has and has not helped before.
- Seated or face down, the base of the skull found by touch and, where used, by ultrasound.
- Local anesthetic, sometimes with a small steroid dose, injected at the greater and, if needed, lesser occipital nerve.
- Response checked in the room — pressing on the spot that was tender, or simply asking what the headache is doing now.
- Home the same day. Track how long relief lasts and report back; that length of time shapes the next decision.
What are the side effects of an occipital nerve block?
Soreness at the injection site and a brief patch of scalp numbness are common and expected. Lightheadedness during the injection is uncommon but can happen. That is why you will be seated or lying down. If steroid is used, a temporary dent or lightening of the skin at the injection site is a known, uncommon effect of repeated steroid given close to the surface. That is one reason this is not a procedure repeated forever without checking whether it is still the right tool.
Frequently asked questions
How is this different from Botox for migraine?
Different mechanism and a different target group. This block numbs a specific nerve to test and treat occipital neuralgia or cervicogenic headache. Migraine treatment is a separate talk, best had once the occipital part has been ruled in or out.
Could my headache actually be coming from my neck?
Often, yes. Joint and disc problems in the upper neck send pain into the head more often than patients are told. That is one reason we examine the neck before treating a headache as a problem purely inside the skull — see cervical radiculopathy for the related nerve-root picture.
How long does relief last?
It varies widely from person to person — some patients get weeks to months from a single block, others get hours. That length of time is itself useful for deciding whether ablation is the right next step; see when injections stop working.
Can this be done if I already have a migraine diagnosis?
You can have migraine and also occipital neuralgia or cervicogenic headache. A block can show whether an occipital part is making headaches worse that were labeled migraine alone, before we consider longer-acting options like radiofrequency ablation.
What if the block does not help?
Then the occipital nerves are not your main driver. We redirect the workup rather than repeat a block that already told us what it needed to. Bring your history to your first visit so we are not starting from zero.
How many times can you have an occipital nerve block?
It depends on how you respond. For many patients, repeating the block when the headache returns is a reasonable, low-risk plan. When steroid is part of the injection, repeated doses close to the surface can dent or lighten the skin. So the plan is checked again rather than repeated forever. Headaches that return on a set schedule are candidates for radiofrequency ablation or, if frequent and severe, peripheral nerve stimulation.
How is occipital neuralgia diagnosed?
History and exam alone struggle, because occipital neuralgia, cervicogenic headache and migraine can hurt in the same places. The typical story is sharp, shocking or burning pain that starts at the base of the skull and spreads forward. The block settles the question. If numbing the occipital nerves substantially relieves the headache within minutes, that pathway is involved. If it barely helps, the pain is coming from somewhere the block cannot reach.
What should I do after an occipital nerve block?
You go home the same day. Soreness at the injection site and a brief patch of numb scalp are common and expected. Your main job is to track how long the relief lasts and report back, because that length of time shapes the next decision. Then look at what keeps irritating the nerve: hours with your neck bent forward over a desk or a phone, and poor sleep, which lowers the threshold for pain.
Related reading
- Occipital neuralgia
- Cervical radiculopathy
- Peripheral nerve stimulation
- Radiofrequency ablation
- Sleep, movement and behavior
We will name which nerve, before we ever suggest heating one
A block is how we confirm the source before offering anything longer-acting. If your headache is not coming from the occipital nerves, you will hear that plainly and we will point you toward the workup that fits.
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Next to St. Louis Lambert International Airport, off I-70 at Woodson Road.
Sources
- Caponnetto V et al. Efficacy and safety of greater occipital nerve block for the treatment of cervicogenic headache: a systematic review. Journal of Headache and Pain, 2021. PubMed 33709864
- Nguyen AT et al. Approaches to Occipital Neuralgia Treatment: A Systematic Review and Case Examples. Journal of Pain Research, 2026. PubMed 41867333
- Slavin KV. Occipital Nerve Stimulation. Neurosurgery Clinics of North America, 2019. PubMed 30898272
- Chowdhury D et al. Role of Greater Occipital Nerve Block in Headache Disorders: A Narrative Review. Annals of Indian Academy of Neurology, 2021. PubMed 34003170